Version 5.4
Mus musculus Gene: Ston2
Summary
InnateDB Gene IDBG-161524.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ston2
Gene Name stonin 2
Synonyms 4933401N24Rik; AI425999; AW544599
Species Mus musculus
Ensembl Gene ENSMUSG00000020961
Encoded Proteins
IDBP-161526
stonin 2
IDBP-621609
stonin 2
IDBP-621612
stonin 2
IDBP-621615
stonin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140022:
This gene encodes a protein which is a membrane protein involved in regulating endocytotic complexes. The protein product is described as one of the clathrin-associated sorting proteins, adaptor molecules which ensure specific proteins are internalized. The encoded protein has also been shown to participate in synaptic vesicle recycling through interaction with synaptotagmin 1 required for neurotransmission. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:91638542-91788387
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000052969 ENSMUSP00000053908
ENSMUST00000111609
ENSMUST00000164713 ENSMUSP00000131098
ENSMUST00000170077 ENSMUSP00000126429
ENSMUST00000170984
ENSMUST00000166967 ENSMUSP00000128561
ENSMUST00000166008
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
GO:0006886 intracellular protein transport
GO:0006897 endocytosis
GO:0007268 synaptic transmission
GO:0016192 vesicle-mediated transport
GO:0030100 regulation of endocytosis
GO:0048488 synaptic vesicle endocytosis
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0008021 synaptic vesicle
GO:0030054 cell junction
GO:0030131 clathrin adaptor complex
GO:0030136 clathrin-coated vesicle
GO:0043005 neuron projection
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000140022
View Gene Order
ENSBTAG00000025308
Not yet available
Cross-References
SwissProt
TrEMBL E9PXP7 E9PYZ0 E9Q9N5
UniProt Splice Variant
Entrez Gene 108800
UniGene Mm.23125 Mm.422039
RefSeq NM_175367 XM_006515373 XM_006515374
OMIM
CCDS CCDS26090
HPRD
IMGT
MGI ID MGI:1918272
MGI Symbol Ston2
EMBL AC154375 AC154709
GenPept
RNA Seq Atlas 108800

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca