Version 5.4
Mus musculus Gene: Nagk
Summary
InnateDB Gene IDBG-161837.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nagk
Gene Name N-acetylglucosamine kinase
Synonyms Gnk
Species Mus musculus
Ensembl Gene ENSMUSG00000034744
Encoded Proteins
IDBP-161839
N-acetylglucosamine kinase
IDBP-253011
N-acetylglucosamine kinase
IDBP-253013
N-acetylglucosamine kinase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124357:
This gene encodes a member of the N-acetylhexosamine kinase family. The encoded protein catalyzes the conversion of N-acetyl-D-glucosamine to N-acetyl-D-glucosamine 6-phosphate, and is the major mammalian enzyme which recovers amino sugars. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:83794982-83803420
Strand Forward strand
Band C3
Transcripts
ENSMUST00000037376 ENSMUSP00000042026
ENSMUST00000113851 ENSMUSP00000109482
ENSMUST00000113850 ENSMUSP00000109481
ENSMUST00000150322
ENSMUST00000146117
ENSMUST00000151147
ENSMUST00000128262
ENSMUST00000141611
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0009384 N-acylmannosamine kinase activity
GO:0045127 N-acetylglucosamine kinase activity
Biological Process
GO:0006044 N-acetylglucosamine metabolic process
GO:0019262 N-acetylneuraminate catabolic process
GO:0046835 carbohydrate phosphorylation
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000124357
View Gene Order
ENSBTAG00000014668
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00520
Amino sugar and nucleotide sugar metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00520
Amino sugar and nucleotide sugar metabolism pathway
INOH
INOH website
Aminosugars metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.190650
RefSeq NM_001164187 NM_019542 XM_006506407
OMIM
CCDS CCDS20286
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca