Mus musculus Gene: Paip2b
Summary
InnateDB Gene IDBG-161969.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Paip2b
Gene Name poly(A) binding protein interacting protein 2B
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000045896
Encoded Proteins
poly(A) binding protein interacting protein 2B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124374:
Most mRNAs, except for histones, contain a 3-prime poly(A) tail. Poly(A)-binding protein (PABP; see MIM 604679) enhances translation by circularizing mRNA through its interaction with the translation initiation factor EIF4G1 (MIM 600495) and the poly(A) tail. Various PABP-binding proteins regulate PABP activity, including PAIP1 (MIM 605184), a translational stimulator, and PAIP2A (MIM 605604) and PAIP2B, translational inhibitors (Derry et al., 2006 [PubMed 17381337]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:83805401-83831741
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000058383 ENSMUSP00000050404
ENSMUST00000125493
ENSMUST00000145593
ENSMUST00000142806
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000900 translation repressor activity, nucleic acid binding
GO:0005515 protein binding
GO:0008143 poly(A) binding
Biological Process
GO:0017148 negative regulation of translation
GO:0045947 negative regulation of translational initiation
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.349160 Mm.404420 Mm.431764 Mm.473572
RefSeq NM_146169 XM_006505970 XM_006505971
OMIM
CCDS CCDS20287
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas