Version 5.4
Bos taurus Gene: PAIP2B
Summary
InnateDB Gene IDBG-631767.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PAIP2B
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014667
Encoded Proteins
IDBP-683328
poly(A) binding protein interacting protein 2B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124374:
Most mRNAs, except for histones, contain a 3-prime poly(A) tail. Poly(A)-binding protein (PABP; see MIM 604679) enhances translation by circularizing mRNA through its interaction with the translation initiation factor EIF4G1 (MIM 600495) and the poly(A) tail. Various PABP-binding proteins regulate PABP activity, including PAIP1 (MIM 605184), a translational stimulator, and PAIP2A (MIM 605604) and PAIP2B, translational inhibitors (Derry et al., 2006 [PubMed 17381337]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:13393546-13397285
Strand Forward strand
Band
Transcripts
ENSBTAT00000019527 ENSBTAP00000019527
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000900 translation repressor activity, nucleic acid binding
GO:0005515 protein binding
Biological Process
GO:0045947 negative regulation of translational initiation
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000124374
View Gene Order
ENSMUSG00000045896
View Gene Order
Cross-References
SwissProt
TrEMBL F1N1G2
UniProt Splice Variant
Entrez Gene 789468
UniGene
RefSeq XM_001256216 XM_002691227 XM_005193874 XM_005212537
HUGO HGNC:29200
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02030408
GenPept
RNA Seq Atlas 789468

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca