Version 5.4
Mus musculus Gene: Htr3b
Summary
InnateDB Gene IDBG-162332.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Htr3b
Gene Name 5-hydroxytryptamine (serotonin) receptor 3B
Synonyms 5-HT3B
Species Mus musculus
Ensembl Gene ENSMUSG00000008590
Encoded Proteins
IDBP-162334
5-hydroxytryptamine (serotonin) receptor 3B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149305:
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:48935008-48964990
Strand Reverse strand
Band A5.3
Transcripts
ENSMUST00000008734 ENSMUSP00000008734
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004993 serotonin receptor activity
GO:0005230 extracellular ligand-gated ion channel activity
GO:0005232 serotonin-activated cation-selective channel activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006812 cation transport
GO:0007210 serotonin receptor signaling pathway
GO:0034220 ion transmembrane transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0045211 postsynaptic membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000149305
View Gene Order
ENSBTAG00000031330
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_25387
Ligand-gated ion channel transport pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9JHJ5
TrEMBL
UniProt Splice Variant
Entrez Gene 57014
UniGene Mm.117131
RefSeq NM_020274
OMIM
CCDS CCDS23160
HPRD
IMGT
MGI ID MGI:1861899
MGI Symbol Htr3b
EMBL AF155045 AF155046 AF155047 AF155048 AF155049 AF155050 AF155051 AF155052 AK085213 BC046990
GenPept AAF73284 AAF73285 AAH46990 BAC39391
RNA Seq Atlas 57014

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca