Version 5.4
Mus musculus Gene: Lap3
Summary
InnateDB Gene IDBG-162362.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lap3
Gene Name leucine aminopeptidase 3
Synonyms 2410015L10Rik; AA410100; Lap; LAP-3; Lapep; Pep-7; Pep-S; Pep7; Peps
Species Mus musculus
Ensembl Gene ENSMUSG00000039682
Encoded Proteins
IDBP-162364
leucine aminopeptidase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000002549:
Gene Information
Type Protein coding
Genomic Location Chromosome 5:45493374-45512674
Strand Forward strand
Band B3
Transcripts
ENSMUST00000046122 ENSMUSP00000040222
ENSMUST00000137699
ENSMUST00000135413
ENSMUST00000131289
ENSMUST00000146811
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004177 aminopeptidase activity
GO:0008233 peptidase activity
GO:0008235 metalloexopeptidase activity
GO:0030145 manganese ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005802 trans-Golgi network
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000002549
View Gene Order
ENSBTAG00000005989
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00480
Glutathione metabolism pathway
mmu00330
Arginine and proline metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00330
Arginine and proline metabolism pathway
hsa00480
Glutathione metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.286830 Mm.456152
RefSeq NM_024434
OMIM
CCDS CCDS19274
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca