Version 5.4
Mus musculus Gene: Kif4
Summary
InnateDB Gene IDBG-162392.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kif4
Gene Name kinesin family member 4
Synonyms AI323435; D330050K22Rik; Kns4
Species Mus musculus
Ensembl Gene ENSMUSG00000034311
Encoded Proteins
IDBP-162394
kinesin family member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000090889:
This gene encodes a member of the kinesin 4 subfamily of kinesin related proteins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:100625737-100727214
Strand Forward strand
Band C3
Transcripts
ENSMUST00000048962 ENSMUSP00000048383
ENSMUST00000156386
ENSMUST00000145319
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005829 cytosol
GO:0005871 kinesin complex
GO:0005874 microtubule
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000090889
View Gene Order
ENSBTAG00000012861
Not yet available
Pathways
NETPATH
REACTOME
REACT_224553
Hemostasis pathway
REACT_257923
Recycling pathway of L1 pathway
REACT_230745
Immune System pathway
REACT_199117
Kinesins pathway
REACT_198649
Factors involved in megakaryocyte development and platelet production pathway
REACT_196550
MHC class II antigen presentation pathway
REACT_261444
Axon guidance pathway
REACT_219680
L1CAM interactions pathway
REACT_229531
Adaptive Immune System pathway
REACT_188576
Developmental Biology pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_121399
MHC class II antigen presentation pathway
REACT_25201
Kinesins pathway
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_22365
Recycling pathway of L1 pathway
REACT_22205
L1CAM interactions pathway
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_604
Hemostasis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P33174
TrEMBL
UniProt Splice Variant
Entrez Gene 16571
UniGene Mm.383091
RefSeq NM_008446 XM_006527856
OMIM
CCDS CCDS30305
HPRD
IMGT
MGI ID MGI:108389
MGI Symbol Kif4
EMBL BC050946 BX005480 BX276129 CH466564 D12646
GenPept AAH50946 BAA02167 CAM15067 CAM17678 EDL14171
RNA Seq Atlas 16571

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca