Version 5.4
Homo sapiens Gene: GPR68
Summary
InnateDB Gene IDBG-16259.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR68
Gene Name G protein-coupled receptor 68
Synonyms GPR12A; OGR1
Species Homo sapiens
Ensembl Gene ENSG00000119714
Encoded Proteins
IDBP-598227
G protein-coupled receptor 68
IDBP-598320
G protein-coupled receptor 68
IDBP-604030
G protein-coupled receptor 68
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:91232532-91253925
Strand Reverse strand
Band q32.11
Transcripts
ENST00000531499 ENSP00000434045
ENST00000529102 ENSP00000432740
ENST00000529300
ENST00000535815 ENSP00000440797
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0006954 inflammatory response
GO:0007186 G-protein coupled receptor signaling pathway
GO:0032024 positive regulation of insulin secretion
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0045656 negative regulation of monocyte differentiation
GO:0071467 cellular response to pH
GO:2001206 positive regulation of osteoclast development
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000047415
View Gene Order
ENSBTAG00000006738
Not yet available
Pathways
NETPATH
REACTOME
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.8882
RefSeq NM_001177676 NM_003485 XM_005268110 XM_005268111 XM_005268112 XM_006720262 XM_006720263
HUGO
OMIM
CCDS CCDS9894
HPRD 03241
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca