Version 5.4
Mus musculus Gene: Neto1
Summary
InnateDB Gene IDBG-162939.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Neto1
Gene Name neuropilin (NRP) and tolloid (TLL)-like 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000050321
Encoded Proteins
IDBP-162941
neuropilin (NRP) and tolloid (TLL)-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166342:
This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in mice encodes a protein that plays a critical role in spatial learning and memory by regulating the function of synaptic N-methyl-D-aspartic acid receptor complexes in the hippocampus. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:86394952-86501897
Strand Forward strand
Band E4
Transcripts
ENSMUST00000058829 ENSMUSP00000057340
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0035255 ionotropic glutamate receptor binding
Biological Process
GO:0007613 memory
GO:0008542 visual learning
GO:0048169 regulation of long-term neuronal synaptic plasticity
GO:0097120 receptor localization to synapse
GO:2000463 positive regulation of excitatory postsynaptic membrane potential
Cellular Component
GO:0014069 postsynaptic density
GO:0030054 cell junction
GO:0032983 kainate selective glutamate receptor complex
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0060076 excitatory synapse
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166342
View Gene Order
ENSBTAG00000012889
Not yet available
Cross-References
SwissProt Q8R4I7
TrEMBL
UniProt Splice Variant
Entrez Gene 246317
UniGene
RefSeq NM_144946 XM_006526480 XM_006526481 XM_006526482
OMIM
CCDS CCDS29387
HPRD
IMGT
MGI ID MGI:2180216
MGI Symbol Neto1
EMBL AF448840 AK032510 AK081325 AY138990 BC051145
GenPept AAH51145 AAM18028 AAN38318 BAC27902 BAC38196
RNA Seq Atlas 246317

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca