Version 5.4
Mus musculus Gene: Plekhg2
Summary
InnateDB Gene IDBG-163140.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Plekhg2
Gene Name pleckstrin homology domain containing, family G (with RhoGef domain) member 2
Synonyms AI194308; Clg; Cslg
Species Mus musculus
Ensembl Gene ENSMUSG00000037552
Encoded Proteins
IDBP-163142
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
IDBP-401175
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
IDBP-401176
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
IDBP-535808
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
IDBP-532983
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
IDBP-539719
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
IDBP-536485
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000090924:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:28359604-28372599
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000094644 ENSMUSP00000092228
ENSMUST00000119990 ENSMUSP00000112881
ENSMUST00000121085 ENSMUSP00000113449
ENSMUST00000128015
ENSMUST00000129145
ENSMUST00000144700 ENSMUSP00000115651
ENSMUST00000147767
ENSMUST00000147362 ENSMUSP00000118217
ENSMUST00000152281 ENSMUSP00000117062
ENSMUST00000147887 ENSMUSP00000122050
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
Biological Process
GO:0032319 regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000090924
View Gene Order
ENSBTAG00000004017
Not yet available
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_209641
NRAGE signals death through JNK pathway
REACT_206918
Signaling by Rho GTPases pathway
REACT_204413
Cell death signalling via NRAGE, NRIF and NADE pathway
REACT_204733
G alpha (12/13) signalling events pathway
REACT_210090
Rho GTPase cycle pathway
REACT_248921
Signalling by NGF pathway
REACT_188257
Signal Transduction pathway
REACT_210847
p75 NTR receptor-mediated signalling pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_13638
NRAGE signals death through JNK pathway
REACT_18407
G alpha (12/13) signalling events pathway
REACT_11051
Rho GTPase cycle pathway
REACT_11061
Signalling by NGF pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_14797
Signaling by GPCR pathway
REACT_13776
p75 NTR receptor-mediated signalling pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_13720
Cell death signalling via NRAGE, NRIF and NADE pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.235700
RefSeq NM_001083912 NM_001290542 NM_138752 XM_006539436 XM_006539437 XM_006539438 XM_006539439 XM_006539440 XM_006539441 XM_006539442
OMIM
CCDS CCDS21040 CCDS52162
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca