Version 5.4
Mus musculus Gene: Kcnip4
Summary
InnateDB Gene IDBG-163191.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kcnip4
Gene Name Kv channel interacting protein 4
Synonyms AV032399; Calp; Calp250; KChIP4; KChIP4a
Species Mus musculus
Ensembl Gene ENSMUSG00000029088
Encoded Proteins
IDBP-163193
Kv channel interacting protein 4
IDBP-163195
Kv channel interacting protein 4
IDBP-163197
Kv channel interacting protein 4
IDBP-627950
Kv channel interacting protein 4
IDBP-627951
Kv channel interacting protein 4
IDBP-725019
IDBP-725167
IDBP-724979
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185774:
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:48389502-49524904
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000101215 ENSMUSP00000098776
ENSMUST00000087395 ENSMUSP00000084656
ENSMUST00000101214 ENSMUSP00000098775
ENSMUST00000172363 ENSMUSP00000127538
ENSMUST00000166924 ENSMUSP00000131276
ENSMUST00000176191 ENSMUSP00000135071
ENSMUST00000175660 ENSMUSP00000135799
ENSMUST00000176978 ENSMUSP00000134758
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005244 voltage-gated ion channel activity
GO:0005267 potassium channel activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0034765 regulation of ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0030425 dendrite
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000185774
View Gene Order
ENSBTAG00000047743
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
betacatenin_nuc_pathway
Regulation of nuclear beta catenin signaling and target gene transcription
Cross-References
SwissProt
TrEMBL Q3UFC0 Q3V060
UniProt Splice Variant
Entrez Gene 80334
UniGene Mm.160172
RefSeq NM_001199244 NM_001199242 NM_001199243 NM_001199245 NM_030265
OMIM
CCDS CCDS57340 CCDS39084 CCDS57339 CCDS57341 CCDS57342
HPRD
IMGT
MGI ID MGI:1933131
MGI Symbol Kcnip4
EMBL AC101004 AC102446 AC103615 AC103623 AC113022 AC116142 AC117559 AC144509 AC144859 AC160458 AC164419 AK133416 AK148685 CH466524
GenPept BAE21645 BAE28641 EDL37638
RNA Seq Atlas 80334

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca