Mus musculus Gene: Tff3
Summary
InnateDB Gene IDBG-163766.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tff3
Gene Name trefoil factor 3, intestinal
Synonyms ITF; mITF
Species Mus musculus
Ensembl Gene ENSMUSG00000024029
Encoded Proteins
trefoil factor 3, intestinal
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160180:
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:31125306-31129646
Strand Reverse strand
Band A3.3
Transcripts
ENSMUST00000024827 ENSMUSP00000024827
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0043434 response to peptide hormone
Cellular Component
GO:0030141 secretory granule
GO:0032579 apical lamina of hyaline layer
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
IL4-mediated signaling events
HIF-1-alpha transcription factor network
Cross-References
SwissProt Q62395
TrEMBL
UniProt Splice Variant
Entrez Gene 21786
UniGene
RefSeq NM_011575
OMIM
CCDS CCDS37544
HPRD
IMGT
MGI ID MGI:104638
MGI Symbol Tff3
EMBL AJ271004 BC011042 D38410 U24220 U24221 U24222 U46858
GenPept AAB92385 AAC52682 AAH11042 BAA07464 CAB65752
RNA Seq Atlas 21786