Mus musculus Gene: Pi4k2b
Summary
InnateDB Gene IDBG-163974.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pi4k2b
Gene Name phosphatidylinositol 4-kinase type 2 beta
Synonyms 2610042N09Rik; 4933409G22Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000029186
Encoded Proteins
phosphatidylinositol 4-kinase type 2 beta
phosphatidylinositol 4-kinase type 2 beta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000038210:
Phosphatidylinositol 4-kinases (PI4Ks) phosphorylate phosphatidylinositol to generate phosphatidylinositol 4-phosphate (PIP), an immediate precursor of several important signaling and scaffolding molecules. PIP itself may also have direct functional and structural roles. PI4K2B is a primarily cytosolic PI4K that is recruited to membranes, where it stimulates phosphatidylinositol 4,5-bisphosphate synthesis (Wei et al., 2002 [PubMed 12324459]).[supplied by OMIM, Jun 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:52741587-52769344
Strand Forward strand
Band C1
Transcripts
ENSMUST00000031081 ENSMUSP00000031081
ENSMUST00000031082 ENSMUSP00000031082
ENSMUST00000131526
ENSMUST00000145825
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004430 1-phosphatidylinositol 4-kinase activity
GO:0005524 ATP binding
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0008150 biological_process
GO:0046854 phosphatidylinositol phosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Synthesis of PIPs at the early endosome membrane pathway
Synthesis of PIPs at the plasma membrane pathway
Synthesis of PIPs at the Golgi membrane pathway
Synthesis of PIPs at the ER membrane pathway
PI Metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Phospholipid metabolism pathway
KEGG
Phosphatidylinositol signaling system pathway
Inositol phosphate metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Synthesis of PIPs at the plasma membrane pathway
Synthesis of PIPs at the early endosome membrane pathway
Synthesis of PIPs at the ER membrane pathway
Synthesis of PIPs at the Golgi membrane pathway
Metabolism of lipids and lipoproteins pathway
PI Metabolism pathway
Phospholipid metabolism pathway
Metabolism pathway
KEGG
Inositol phosphate metabolism pathway
Phosphatidylinositol signaling system pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.248647 Mm.468296
RefSeq NM_025951 NM_028744
OMIM
CCDS CCDS19287 CCDS39086
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas