Version 5.4
Mus musculus Gene: Cited1
Summary
InnateDB Gene IDBG-164976.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cited1
Gene Name Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
Synonyms AI316840; AU019144; Msg1
Species Mus musculus
Ensembl Gene ENSMUSG00000051159
Encoded Proteins
IDBP-164978
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
IDBP-164980
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
IDBP-541433
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
IDBP-539545
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
IDBP-532149
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125931:
This gene encodes a member of the CREB-binding protein/p300-interacting transactivator with Asp/Glu-rich C-terminal domain (CITED) family of proteins. The encoded protein, also known as melanocyte-specific gene 1, may function as a transcriptional coactivator and may play a role in pigmentation of melanocytes. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:102247381-102252181
Strand Reverse strand
Band D
Transcripts
ENSMUST00000050551 ENSMUSP00000051789
ENSMUST00000101336 ENSMUSP00000098890
ENSMUST00000134887 ENSMUSP00000117702
ENSMUST00000130589 ENSMUSP00000119123
ENSMUST00000136277 ENSMUSP00000114269
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0050693 LBD domain binding
GO:0070410 co-SMAD binding
Biological Process
GO:0000578 embryonic axis specification
GO:0001570 vasculogenesis
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001890 placenta development
GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006913 nucleocytoplasmic transport
GO:0006915 apoptotic process
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007420 brain development
GO:0010628 positive regulation of gene expression
GO:0030318 melanocyte differentiation
GO:0032496 response to lipopolysaccharide
GO:0032868 response to insulin
GO:0034097 response to cytokine
GO:0034341 response to interferon-gamma
GO:0042438 melanin biosynthetic process
GO:0043473 pigmentation
GO:0043524 negative regulation of neuron apoptotic process
GO:0043627 response to estrogen
GO:0045668 negative regulation of osteoblast differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0051591 response to cAMP
GO:0060395 SMAD protein signal transduction
GO:0060711 labyrinthine layer development
GO:0060712 spongiotrophoblast layer development
GO:0070555 response to interleukin-1
GO:0070669 response to interleukin-2
GO:0070670 response to interleukin-4
GO:0070741 response to interleukin-6
GO:0071104 response to interleukin-9
GO:0071105 response to interleukin-11
GO:0071107 response to parathyroid hormone
GO:0071559 response to transforming growth factor beta
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000125931
View Gene Order
ENSBTAG00000045925
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_7
TGF_beta_Receptor pathway
REACTOME
KEGG
INOH
PID NCI
smad2_3nuclearpathway
Regulation of nuclear SMAD2/3 signaling
Cross-References
SwissProt P97769
TrEMBL F6YUL1 F6ZC52 Q3UGA1
UniProt Splice Variant
Entrez Gene 12705
UniGene
RefSeq NM_001276466 NM_001276473 NM_007709
OMIM
CCDS CCDS30322
HPRD
IMGT
MGI ID MGI:108023
MGI Symbol Cited1
EMBL AK148042 AL954850 BC052030 CH466564 U65091
GenPept AAC53048 AAH52030 BAE28308 EDL14126
RNA Seq Atlas 12705

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca