Version 5.4
Mus musculus Gene: Slc24a4
Summary
InnateDB Gene IDBG-165526.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc24a4
Gene Name solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000041771
Encoded Proteins
IDBP-165528
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
IDBP-538459
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
IDBP-541192
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140090:
This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:102128733-102267091
Strand Forward strand
Band E
Transcripts
ENSMUST00000079020 ENSMUSP00000078030
ENSMUST00000159329 ENSMUSP00000124513
ENSMUST00000161325 ENSMUSP00000125012
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005432 calcium:sodium antiporter activity
GO:0008273 calcium, potassium:sodium antiporter activity
GO:0015293 symporter activity
Biological Process
GO:0006813 potassium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0007608 sensory perception of smell
GO:0035725 sodium ion transmembrane transport
GO:0050896 response to stimulus
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
GO:0097186 amelogenesis
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000140090
View Gene Order
ENSBTAG00000006620
Not yet available
Pathways
NETPATH
REACTOME
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_251788
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_236234
Sodium/Calcium exchangers pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19320
Sodium/Calcium exchangers pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 238384
UniGene Mm.312448
RefSeq NM_172152
OMIM
CCDS CCDS26117
HPRD
IMGT
MGI ID MGI:2447362
MGI Symbol Slc24a4
EMBL
GenPept
RNA Seq Atlas 238384

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca