Version 5.4
Homo sapiens Gene: SLC24A4
Summary
InnateDB Gene IDBG-16940.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC24A4
Gene Name solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000140090
Encoded Proteins
IDBP-243948
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
IDBP-602508
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
IDBP-592639
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
IDBP-602175
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
IDBP-599779
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:92322581-92501483
Strand Forward strand
Band q32.12
Transcripts
ENST00000393265 ENSP00000376948
ENST00000531433 ENSP00000433302
ENST00000532405 ENSP00000431840
ENST00000554461 ENSP00000452099
ENST00000525557 ENSP00000432464
ENST00000554925
ENST00000556739
ENST00000526482
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008273 calcium, potassium:sodium antiporter activity
GO:0015293 symporter activity
Biological Process
GO:0006811 ion transport
GO:0006813 potassium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0007608 sensory perception of smell
GO:0035725 sodium ion transmembrane transport
GO:0050896 response to stimulus
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
GO:0097186 amelogenesis
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000041771
View Gene Order
ENSBTAG00000006620
Not yet available
Pathways
NETPATH
REACTOME
REACT_19320
Sodium/Calcium exchangers pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.385530
RefSeq NM_153646 NM_153647 NM_153648 XM_005267341
HUGO
OMIM
CCDS CCDS45155 CCDS45156 CCDS9903
HPRD 15353
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca