Mus musculus Gene: Pmm1
Summary
InnateDB Gene IDBG-165689.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pmm1
Gene Name phosphomannomutase 1
Synonyms C77612
Species Mus musculus
Ensembl Gene ENSMUSG00000022474
Encoded Proteins
phosphomannomutase 1
phosphomannomutase 1
phosphomannomutase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100417:
Phosphomannomutase catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:81951108-81960930
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000023112 ENSMUSP00000023112
ENSMUST00000071462 ENSMUSP00000071405
ENSMUST00000129406
ENSMUST00000155781 ENSMUSP00000115551
ENSMUST00000125593
ENSMUST00000147645
ENSMUST00000147442
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004615 phosphomannomutase activity
GO:0046872 metal ion binding
Biological Process
GO:0006013 mannose metabolic process
GO:0008152 metabolic process
GO:0009298 GDP-mannose biosynthetic process
GO:0019307 mannose biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Synthesis of substrates in N-glycan biosythesis pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Synthesis of GDP-mannose pathway
Asparagine N-linked glycosylation pathway
KEGG
Amino sugar and nucleotide sugar metabolism pathway
Fructose and mannose metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Synthesis of GDP-mannose pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
Metabolism of proteins pathway
KEGG
Amino sugar and nucleotide sugar metabolism pathway
Fructose and mannose metabolism pathway
INOH
Fructose Mannose metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL D6RG76
UniProt Splice Variant
Entrez Gene 29858
UniGene Mm.18939
RefSeq NM_001282040 NM_013872
OMIM
CCDS CCDS27678 CCDS70650
HPRD
IMGT
MGI ID MGI:1353418
MGI Symbol Pmm1
EMBL AC102103 CH466550
GenPept EDL04543
RNA Seq Atlas 29858