InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Rqcd1

Summary

InnateDB Gene

IDBG-167354.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rqcd1

Gene Name

rcd1 (required for cell differentiation) homolog 1 (S. pombe)

Synonyms

2610007F23Rik; AI593551; Fl10

Species

Mus musculus

Ensembl Gene

ENSMUSG00000026174

Encoded Proteins

IDBP-167356

rcd1 (required for cell differentiation) homolog 1 (S. pombe)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144580:
This gene encodes a member of the highly conserved RCD1 protein family. The encoded protein is a transcriptional cofactor and a core protein of the CCR4-NOT complex. It may be involved in signal transduction as well as retinoic acid-regulated cell differentiation and development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:74506058-74530842

Strand

Forward strand

Band

Transcripts

ENSMUST00000087215	ENSMUSP00000084466
ENSMUST00000137100
ENSMUST00000147810

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006417	regulation of translation
GO:0019221	cytokine-mediated signaling pathway
GO:0031047	gene silencing by RNA
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway
GO:2000327	positive regulation of ligand-dependent nuclear receptor transcription coactivator activity

Cellular Component

GO:0000932	cytoplasmic mRNA processing body
GO:0005634	nucleus
GO:0016020	membrane
GO:0030014	CCR4-NOT complex

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000144580

View Gene Order

ENSBTAG00000003807

Not yet available

Pathways

NETPATH

REACTOME

REACT_244119

Deadenylation of mRNA pathway

REACT_233572

Gene Expression pathway

REACT_235784

Deadenylation-dependent mRNA decay pathway

KEGG

mmu03018

RNA degradation pathway

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_20514

Deadenylation of mRNA pathway

REACT_20639

Deadenylation-dependent mRNA decay pathway

REACT_71

Gene Expression pathway

REACT_224454

Deadenylation of mRNA pathway

REACT_226022

Gene Expression pathway

REACT_203426

Deadenylation-dependent mRNA decay pathway

KEGG

hsa03018

RNA degradation pathway

INOH

PID NCI

Cross-References

SwissProt

Q9JKY0

TrEMBL

UniProt Splice Variant

Entrez Gene

58184

UniGene

Mm.291708

RefSeq

NM_021383 XM_006496171

OMIM

CCDS

CCDS35615

HPRD

IMGT

MGI ID

MGI:1928902

MGI Symbol

Rqcd1

EMBL

AF221849 AK005025 BC050898 BC051948

GenPept

AAF61701 AAH50898 AAH51948 BAB23752

RNA Seq Atlas

58184