Version 5.4
Homo sapiens Gene: LRP1B
Summary
InnateDB Gene IDBG-71206.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LRP1B
Gene Name low density lipoprotein receptor-related protein 1B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000168702
Encoded Proteins
IDBP-71210
low density lipoprotein receptor-related protein 1B
IDBP-386237
low density lipoprotein receptor-related protein 1B
IDBP-386238
low density lipoprotein receptor-related protein 1B
IDBP-386239
low density lipoprotein receptor-related protein 1B
IDBP-811131
low density lipoprotein receptor-related protein 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary LRP1B belongs to the low density lipoprotein (LDL) receptor gene family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands (Liu et al., 2001 [PubMed 11384978]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:140231423-142131701
Strand Reverse strand
Band q22.2
Transcripts
ENST00000389484 ENSP00000374135
ENST00000437977 ENSP00000415052
ENST00000442974 ENSP00000393859
ENST00000434794 ENSP00000413239
ENST00000486364
ENST00000618808 ENSP00000478868
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005041 low-density lipoprotein receptor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0015031 protein transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043235 receptor complex
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000049252
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.614222 Hs.656461
RefSeq NM_018557
HUGO
OMIM
CCDS CCDS2182
HPRD 16383
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca