Mus musculus Gene: B3galt4
Summary
InnateDB Gene IDBG-168558.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol B3galt4
Gene Name UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
Synonyms Gal-T2; Galt2
Species Mus musculus
Ensembl Gene ENSMUSG00000067370
Encoded Proteins
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000235863:
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is oriented telomere to centromere in close proximity to the ribosomal protein S18 gene. The functionality of the encoded protein is limited to ganglioseries glycolipid biosynthesis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:33949909-33951477
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000087543 ENSMUSP00000084823
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008378 galactosyltransferase activity
GO:0047915 ganglioside galactosyltransferase activity
Biological Process
GO:0006486 protein glycosylation
GO:0008150 biological_process
Cellular Component
GO:0000139 Golgi membrane
GO:0005575 cellular_component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Glycosphingolipid biosynthesis pathway
Other types of O-glycan biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Glycosphingolipid biosynthesis pathway
Other types of O-glycan biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q9Z0F0
TrEMBL
UniProt Splice Variant
Entrez Gene 54218
UniGene Mm.11132
RefSeq NM_019420
OMIM
CCDS CCDS28638
HPRD
IMGT
MGI ID MGI:1859517
MGI Symbol B3galt4
EMBL AB039164 AB039165 AB039166 AB039167 AB039168 AB039169 AB039170 AB039171 AB039172 AF082504 AF100956 AF110520
GenPept AAC69622 AAC69897 AAC97977 BAB68688 BAB68689 BAB68690 BAB68691 BAB68692 BAB68693 BAB68694 BAB68695 BAB68696
RNA Seq Atlas 54218