Bos taurus Gene: B3GALT4
Summary
InnateDB Gene IDBG-628985.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol B3GALT4
Gene Name beta-1,3-galactosyltransferase 4 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000025669
Encoded Proteins
beta-1,3-galactosyltransferase 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000235863:
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is oriented telomere to centromere in close proximity to the ribosomal protein S18 gene. The functionality of the encoded protein is limited to ganglioseries glycolipid biosynthesis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:7394229-7395863
Strand Forward strand
Band
Transcripts
ENSBTAT00000036248 ENSBTAP00000036110
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008378 galactosyltransferase activity
GO:0016740 transferase activity
GO:0016757 transferase activity, transferring glycosyl groups
Biological Process
GO:0006486 protein glycosylation
Cellular Component
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Homo sapiens
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Glycosphingolipid biosynthesis pathway
Other types of O-glycan biosynthesis pathway
Glycosphingolipid biosynthesis pathway
Other types of O-glycan biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q2HJA3
UniProt Splice Variant
Entrez Gene 768038
UniGene Bt.67515
RefSeq NM_001077097 XM_005223269 XM_005223270
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC113234 DAAA02054898
GenPept AAI13235
RNA Seq Atlas 768038