Mus musculus Gene: Slc35d1
Summary
InnateDB Gene IDBG-168963.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc35d1
Gene Name solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000028521
Encoded Proteins
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116704:
Glycosylation of cellular glycoconjugates occurs in the endoplasmic reticulum (ER) and Golgi compartment, and requires transport of nucleotide sugars from the cytosol into the lumen of the ER and Golgi by specific transporters. The protein encoded by this gene resides in the ER, and transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to the ER lumen. It may participate in glucuronidation and/or chondroitin sulfate biosynthesis. Mutations in this gene are associated with Schneckenbecken dysplasia.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:103170649-103215164
Strand Reverse strand
Band C6
Transcripts
ENSMUST00000036195 ENSMUSP00000037617
ENSMUST00000094947 ENSMUSP00000092554
ENSMUST00000150285 ENSMUSP00000122124
ENSMUST00000154845
ENSMUST00000183432 ENSMUSP00000138926
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity
Biological Process
GO:0015781 pyrimidine nucleotide-sugar transport
GO:0030206 chondroitin sulfate biosynthetic process
GO:0048706 embryonic skeletal system development
GO:0090481 pyrimidine nucleotide-sugar transmembrane transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Transport of nucleotide sugars pathway
Transport of vitamins, nucleosides, and related molecules pathway
Formation of the active cofactor, UDP-glucuronate pathway
Glucuronidation pathway
Transmembrane transport of small molecules pathway
Phase II conjugation pathway
Metabolism pathway
Biological oxidations pathway
SLC-mediated transmembrane transport pathway
SLC-mediated transmembrane transport pathway
Formation of the active cofactor, UDP-glucuronate pathway
Transport of nucleotide sugars pathway
Transmembrane transport of small molecules pathway
Biological oxidations pathway
Transport of vitamins, nucleosides, and related molecules pathway
Metabolism pathway
Phase II conjugation pathway
Glucuronidation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q8BX24
UniProt Splice Variant
Entrez Gene 242585
UniGene Mm.474839
RefSeq NM_177732 XM_006503080
OMIM
CCDS CCDS18409
HPRD
IMGT
MGI ID MGI:2140361
MGI Symbol Slc35d1
EMBL AK049180 AL772338
GenPept BAC33591
RNA Seq Atlas 242585