Version 5.4
Bos taurus Gene: SLC35D2
Summary
InnateDB Gene IDBG-638130.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC35D2
Gene Name UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter
Synonyms SLC35D2
Species Bos taurus
Ensembl Gene ENSBTAG00000005445
Encoded Proteins
IDBP-690171
UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116704:
Glycosylation of cellular glycoconjugates occurs in the endoplasmic reticulum (ER) and Golgi compartment, and requires transport of nucleotide sugars from the cytosol into the lumen of the ER and Golgi by specific transporters. The protein encoded by this gene resides in the ER, and transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to the ER lumen. It may participate in glucuronidation and/or chondroitin sulfate biosynthesis. Mutations in this gene are associated with Schneckenbecken dysplasia.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:78601770-78644543
Strand Forward strand
Band
Transcripts
ENSBTAT00000007164 ENSBTAP00000007164
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity
Biological Process
GO:0006810 transport
GO:0008643 carbohydrate transport
GO:0015781 pyrimidine nucleotide-sugar transport
GO:0030206 chondroitin sulfate biosynthetic process
GO:0048706 embryonic skeletal system development
GO:0090481 pyrimidine nucleotide-sugar transmembrane transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000116704
View Gene Order
ENSMUSG00000028521
View Gene Order
Pathways
NETPATH
REACTOME
REACT_222460
SLC-mediated transmembrane transport pathway
REACT_214113
Formation of the active cofactor, UDP-glucuronate pathway
REACT_217642
Transport of nucleotide sugars pathway
REACT_223103
Transmembrane transport of small molecules pathway
REACT_218176
Biological oxidations pathway
REACT_218813
Transport of vitamins, nucleosides, and related molecules pathway
REACT_219139
Metabolism pathway
REACT_213008
Phase II conjugation pathway
REACT_204452
Glucuronidation pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22151
Transport of nucleotide sugars pathway
REACT_22285
Transport of vitamins, nucleosides, and related molecules pathway
REACT_6737
Formation of the active cofactor, UDP-glucuronate pathway
REACT_6784
Glucuronidation pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_6959
Phase II conjugation pathway
REACT_111217
Metabolism pathway
REACT_13433
Biological oxidations pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.58895
RefSeq NM_001082459
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca