Version 5.4
Mus musculus Gene: Dach2
Summary
InnateDB Gene IDBG-168970.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dach2
Gene Name dachshund 2 (Drosophila)
Synonyms 9430028N04Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000025592
Encoded Proteins
IDBP-168972
dachshund 2 (Drosophila)
IDBP-254001
dachshund 2 (Drosophila)
IDBP-254005
dachshund 2 (Drosophila)
IDBP-254007
dachshund 2 (Drosophila)
IDBP-254009
dachshund 2 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000126733:
This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:113297510-113836386
Strand Forward strand
Band E1
Transcripts
ENSMUST00000067219 ENSMUSP00000064393
ENSMUST00000113382 ENSMUSP00000109009
ENSMUST00000113380 ENSMUSP00000109007
ENSMUST00000113379 ENSMUSP00000109006
ENSMUST00000113378 ENSMUSP00000109005
ENSMUST00000146539
ENSMUST00000141552
ENSMUST00000123974
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0046545 development of primary female sexual characteristics
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000126733
View Gene Order
ENSBTAG00000044037
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.487965 Mm.79760
RefSeq NM_001142570 NM_001289732 NM_033605
OMIM
CCDS CCDS30363 CCDS53175
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca