Version 5.4
Mus musculus Gene: Ska3
Summary
InnateDB Gene IDBG-168988.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ska3
Gene Name spindle and kinetochore associated complex subunit 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000021965
Encoded Proteins
IDBP-168990
RIKEN cDNA F630043A04 gene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165480:
This gene encodes a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. The encoded protein localizes to the outer kinetechore and may be required for normal chromosome segregation and cell division. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:57806561-57826163
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000022536 ENSMUSP00000022536
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
GO:0031110 regulation of microtubule polymerization or depolymerization
Cellular Component
GO:0000940 condensed chromosome outer kinetochore
GO:0005737 cytoplasm
GO:0005876 spindle microtubule
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000165480
View Gene Order
ENSBTAG00000003314
Not yet available
Cross-References
SwissProt Q8C263
TrEMBL
UniProt Splice Variant
Entrez Gene 219114
UniGene Mm.30173 Mm.490583
RefSeq NM_198605
OMIM
CCDS CCDS27160
HPRD
IMGT
MGI ID MGI:3041235
MGI Symbol Ska3
EMBL AK089223 BC117500 BC117501
GenPept AAI17501 AAI17502 BAC40798
RNA Seq Atlas 219114

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca