Version 5.4
Bos taurus Gene: SKA3
Summary
InnateDB Gene IDBG-631135.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SKA3
Gene Name Spindle and kinetochore-associated protein 3
Synonyms C12H13ORF3
Species Bos taurus
Ensembl Gene ENSBTAG00000003314
Encoded Proteins
IDBP-682658
Spindle and kinetochore-associated protein 3
IDBP-682659
Spindle and kinetochore-associated protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165480:
This gene encodes a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. The encoded protein localizes to the outer kinetechore and may be required for normal chromosome segregation and cell division. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:35841563-35854986
Strand Forward strand
Band
Transcripts
ENSBTAT00000004289 ENSBTAP00000004289
ENSBTAT00000063452 ENSBTAP00000056583
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007049 cell cycle
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
GO:0031110 regulation of microtubule polymerization or depolymerization
GO:0051301 cell division
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000777 condensed chromosome kinetochore
GO:0000940 condensed chromosome outer kinetochore
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0005876 spindle microtubule
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000165480
View Gene Order
ENSMUSG00000021965
View Gene Order
Cross-References
SwissProt A8PUI7
TrEMBL
UniProt Splice Variant
Entrez Gene 509921
UniGene Bt.30182 Bt.68726
RefSeq NM_001110067
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC112513 CK947368
GenPept AAI12514
RNA Seq Atlas 509921

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca