Version 5.4
Mus musculus Gene: Sytl4
Summary
InnateDB Gene IDBG-170513.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sytl4
Gene Name synaptotagmin-like 4
Synonyms Gph; Slp4
Species Mus musculus
Ensembl Gene ENSMUSG00000031255
Encoded Proteins
IDBP-170515
synaptotagmin-like 4
IDBP-254168
synaptotagmin-like 4
IDBP-254170
synaptotagmin-like 4
IDBP-622956
synaptotagmin-like 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102362:
This gene encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:133936385-133981812
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000033608 ENSMUSP00000033608
ENSMUST00000113297 ENSMUSP00000108922
ENSMUST00000113294 ENSMUSP00000108919
ENSMUST00000174091
ENSMUST00000174542 ENSMUSP00000134030
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005543 phospholipid binding
GO:0008270 zinc ion binding
GO:0017137 Rab GTPase binding
GO:0042043 neurexin family protein binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006887 exocytosis
GO:0045921 positive regulation of exocytosis
GO:0046676 negative regulation of insulin secretion
GO:0050714 positive regulation of protein secretion
GO:0071985 multivesicular body sorting pathway
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005813 centrosome
GO:0019898 extrinsic component of membrane
GO:0030141 secretory granule
GO:0030658 transport vesicle membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000102362
View Gene Order
ENSBTAG00000005724
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.38674
RefSeq NM_001290717 NM_001290718 NM_001290719 NM_013757 XM_006528551 XM_006528552 XM_006528553
OMIM
CCDS CCDS30388 CCDS72429
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca