Version 5.4
Mus musculus Gene: Poll
Summary
InnateDB Gene IDBG-170875.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Poll
Gene Name polymerase (DNA directed), lambda
Synonyms 1110003P06Rik; AV007317
Species Mus musculus
Ensembl Gene ENSMUSG00000025218
Encoded Proteins
IDBP-170877
polymerase (DNA directed), lambda
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166169:
This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:45552275-45560531
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000026239 ENSMUSP00000026239
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0003887 DNA-directed DNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0006261 DNA-dependent DNA replication
GO:0006287 base-excision repair, gap-filling
GO:0006289 nucleotide-excision repair
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166169
View Gene Order
ENSBTAG00000003576
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03410
Base excision repair pathway
mmu03450
Non-homologous end-joining pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03450
Non-homologous end-joining pathway
hsa03410
Base excision repair pathway
INOH
PID NCI
dnapk_pathway
DNA-PK pathway in nonhomologous end joining
Cross-References
SwissProt Q9QXE2
TrEMBL
UniProt Splice Variant
Entrez Gene 56626
UniGene
RefSeq NM_020032 XM_006527232
OMIM
CCDS CCDS29861
HPRD
IMGT
MGI ID MGI:1889000
MGI Symbol Poll
EMBL AF176099 AJ131889 AK003392 BC004767
GenPept AAF27553 AAH04767 BAB22759 CAB65241
RNA Seq Atlas 56626

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca