Mus musculus Gene: Cerk | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-171293.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | Cerk | ||||||||||||
Gene Name | ceramide kinase | ||||||||||||
Synonyms | |||||||||||||
Species | Mus musculus | ||||||||||||
Ensembl Gene | ENSMUSG00000035891 | ||||||||||||
Encoded Proteins |
ceramide kinase
ceramide kinase
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100422:
CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]).[supplied by OMIM, Mar 2008] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 15:86139128-86186141 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | E2 | ||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Orphan transporters pathway
Glycosphingolipid metabolism pathway
Metabolism pathway
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
Transmembrane transport of small molecules pathway
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KEGG |
Sphingolipid metabolism pathway
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INOH | |||||||||||||
PID NCI | |||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Glycosphingolipid metabolism pathway
Sphingolipid metabolism pathway
Transmembrane transport of small molecules pathway
Metabolism of lipids and lipoproteins pathway
Orphan transporters pathway
Metabolism pathway
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KEGG |
Sphingolipid metabolism pathway
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INOH | |||||||||||||
PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | D3Z254 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 223753 | ||||||||||||
UniGene | Mm.222685 Mm.398183 Mm.409270 | ||||||||||||
RefSeq | NM_145475 XM_006520831 | ||||||||||||
OMIM | |||||||||||||
CCDS | CCDS27728 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
MGI ID | MGI:2386052 | ||||||||||||
MGI Symbol | Cerk | ||||||||||||
EMBL | AC116764 | ||||||||||||
GenPept | |||||||||||||
RNA Seq Atlas | 223753 | ||||||||||||