InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Inha

Summary

InnateDB Gene

IDBG-171659.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Inha

Gene Name

inhibin alpha

Synonyms

AW555078

Species

Mus musculus

Ensembl Gene

ENSMUSG00000032968

Encoded Proteins

IDBP-171661

inhibin alpha

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123999:
This gene encodes the alpha subunit of inhibins A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion.[provided by RefSeq, Dec 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:75507077-75510366

Strand

Forward strand

Band

Transcripts

ENSMUST00000037330

ENSMUSP00000040310

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005179	hormone activity
GO:0005515	protein binding
GO:0008083	growth factor activity
GO:0034711	inhibin binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0001541	ovarian follicle development
GO:0008584	male gonad development
GO:0042127	regulation of cell proliferation
GO:0042541	hemoglobin biosynthetic process
GO:0046882	negative regulation of follicle-stimulating hormone secretion
GO:0051726	regulation of cell cycle

Cellular Component

GO:0001750	photoreceptor outer segment
GO:0001917	photoreceptor inner segment
GO:0005615	extracellular space
GO:0034673	inhibin-betaglycan-ActRII complex
GO:0043025	neuronal cell body
GO:0043512	inhibin A complex