Version 5.4
Bos taurus Gene: INHA
Summary
InnateDB Gene IDBG-644083.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INHA
Gene Name Inhibin alpha chain
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009972
Encoded Proteins
IDBP-696691
Inhibin alpha chain
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123999:
This gene encodes the alpha subunit of inhibins A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion.[provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:108226858-108229830
Strand Forward strand
Band
Transcripts
ENSBTAT00000013154 ENSBTAP00000013154
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005179 hormone activity
GO:0005515 protein binding
GO:0008083 growth factor activity
Biological Process
GO:0042127 regulation of cell proliferation
GO:0042541 hemoglobin biosynthetic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005576 extracellular region
GO:0034673 inhibin-betaglycan-ActRII complex
GO:0043512 inhibin A complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000123999
View Gene Order
ENSMUSG00000032968
View Gene Order
Pathways
NETPATH
REACTOME
REACT_210701
Peptide hormone metabolism pathway
REACT_218655
Glycoprotein hormones pathway
REACT_220432
Peptide hormone biosynthesis pathway
REACT_213782
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_15398
Glycoprotein hormones pathway
REACT_15452
Peptide hormone biosynthesis pathway
REACT_17015
Metabolism of proteins pathway
REACT_160078
Peptide hormone metabolism pathway
REACT_247926
Metabolism of proteins pathway
REACT_206913
Peptide hormone metabolism pathway
REACT_259994
Glycoprotein hormones pathway
REACT_242718
Peptide hormone biosynthesis pathway
KEGG
INOH
INOH website
GPCR signaling pathway
INOH website
TGF-beta signaling pathway
INOH website
BMP2 signaling pathway
INOH website
GPCR signaling pathway
INOH website
BMP2 signaling pathway
INOH website
TGF-beta signaling pathway
PID NCI
Cross-References
SwissProt P07994
TrEMBL
UniProt Splice Variant
Entrez Gene 281254
UniGene Bt.36723
RefSeq NM_174094
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC109837 M13273 U16237
GenPept AAA97414 AAB60262 AAI09838
RNA Seq Atlas 281254

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca