Version 5.4
Mus musculus Gene: Mag
Summary
InnateDB Gene IDBG-171670.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mag
Gene Name myelin-associated glycoprotein
Synonyms Gma; siglec-4a
Species Mus musculus
Ensembl Gene ENSMUSG00000036634
Encoded Proteins
IDBP-171674
myelin-associated glycoprotein
IDBP-789464
myelin-associated glycoprotein
IDBP-789465
myelin-associated glycoprotein
IDBP-789469
myelin-associated glycoprotein
IDBP-789470
myelin-associated glycoprotein
IDBP-789473
myelin-associated glycoprotein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105695:
The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:30899176-30914873
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000040548 ENSMUSP00000041464
ENSMUST00000187137 ENSMUSP00000139564
ENSMUST00000191081 ENSMUSP00000139881
ENSMUST00000188569 ENSMUSP00000140526
ENSMUST00000186422
ENSMUST00000190638 ENSMUSP00000140578
ENSMUST00000190950 ENSMUSP00000139861
ENSMUST00000191486
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0021762 substantia nigra development
Cellular Component
GO:0016021 integral component of membrane
GO:0033270 paranode region of axon
GO:0043209 myelin sheath
GO:0043220 Schmidt-Lanterman incisure
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000105695
View Gene Order
ENSBTAG00000017044
Not yet available
Pathways
NETPATH
REACTOME
REACT_222662
p75NTR regulates axonogenesis pathway
REACT_224553
Hemostasis pathway
REACT_203657
Axonal growth inhibition (RHOA activation) pathway
REACT_225233
Cell surface interactions at the vascular wall pathway
REACT_211508
Basigin interactions pathway
REACT_248921
Signalling by NGF pathway
REACT_188257
Signal Transduction pathway
REACT_210847
p75 NTR receptor-mediated signalling pathway
KEGG
mmu04514
Cell adhesion molecules (CAMs) pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_12560
Basigin interactions pathway
REACT_12051
Cell surface interactions at the vascular wall pathway
REACT_13815
Axonal growth inhibition (RHOA activation) pathway
REACT_11061
Signalling by NGF pathway
REACT_13620
p75NTR regulates axonogenesis pathway
REACT_13776
p75 NTR receptor-mediated signalling pathway
REACT_111102
Signal Transduction pathway
REACT_604
Hemostasis pathway
KEGG
hsa04514
Cell adhesion molecules (CAMs) pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_010758 XM_006539589 XM_006539590 XM_006539591 XM_006539592
OMIM
CCDS CCDS21115
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca