Version 5.4
Mus musculus Gene: Palm3
Summary
InnateDB Gene IDBG-173238.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Palm3
Gene Name paralemmin 3
Synonyms 4432412L15Rik; AL024300
Species Mus musculus
Ensembl Gene ENSMUSG00000047986
Encoded Proteins
IDBP-173240
paralemmin 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 21187075
Palm3 is a LPS inducible gene that functions as an adaptor protein for Tlr4 signaling. Palm3 interacts with Sigirr to negatively regulate TLR signaling.
InnateDB Annotation from Orthologs
Summary
PMID 21187075
[Homo sapiens] PALM3 is a LPS inducible gene that functions as an adaptor protein for TLR4 signalling. PALM3 interacts with SIGIRR to negatively regulate TLR signalling.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187867:
Gene Information
Type Protein coding
Genomic Location Chromosome 8:84021471-84030295
Strand Forward strand
Band C2
Transcripts
ENSMUST00000055077 ENSMUSP00000051396
ENSMUST00000142367
ENSMUST00000154171
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0001960 negative regulation of cytokine-mediated signaling pathway
GO:0008063 Toll signaling pathway
GO:0032496 response to lipopolysaccharide
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000187867
View Gene Order
ENSBTAG00000046744
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.250943
RefSeq NM_028877 XM_006531429
OMIM
CCDS CCDS40405
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca