Version 5.4
Bos taurus Gene: PALM3
Summary
InnateDB Gene IDBG-642730.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PALM3
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000046744
Encoded Proteins
IDBP-695220
paralemmin 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 21187075
[Homo sapiens] PALM3 is a LPS inducible gene that functions as an adaptor protein for TLR4 signalling. PALM3 interacts with SIGIRR to negatively regulate TLR signalling.
PMID 21187075
[Mus musculus] Palm3 is a LPS inducible gene that functions as an adaptor protein for Tlr4 signaling. Palm3 interacts with Sigirr to negatively regulate TLR signaling.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187867:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:12733954-12742933
Strand Forward strand
Band
Transcripts
ENSBTAT00000064936 ENSBTAP00000053902
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001960 negative regulation of cytokine-mediated signaling pathway
GO:0008063 Toll signaling pathway
GO:0032496 response to lipopolysaccharide
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000187867
View Gene Order
ENSMUSG00000047986
View Gene Order
Cross-References
SwissProt
TrEMBL G3MWK1
UniProt Splice Variant
Entrez Gene 527118
UniGene
RefSeq
HUGO HGNC:33274
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02019350
GenPept
RNA Seq Atlas 527118

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca