Version 5.4
Mus musculus Gene: Nrd1
Summary
InnateDB Gene IDBG-173849.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nrd1
Gene Name nardilysin, N-arginine dibasic convertase, NRD convertase 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000053510
Encoded Proteins
IDBP-173851
nardilysin, N-arginine dibasic convertase, NRD convertase 1
IDBP-173853
nardilysin, N-arginine dibasic convertase, NRD convertase 1
IDBP-268336
nardilysin, N-arginine dibasic convertase, NRD convertase 1
IDBP-536529
nardilysin, N-arginine dibasic convertase, NRD convertase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000078618:
This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:109000655-109061777
Strand Forward strand
Band C7
Transcripts
ENSMUST00000102736 ENSMUSP00000099797
ENSMUST00000065977 ENSMUSP00000068328
ENSMUST00000106644 ENSMUSP00000102255
ENSMUST00000125645 ENSMUSP00000122808
ENSMUST00000155228
ENSMUST00000150177
ENSMUST00000143604
ENSMUST00000150784
ENSMUST00000148444
ENSMUST00000143015
ENSMUST00000150796
ENSMUST00000125063
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000078618
View Gene Order
ENSBTAG00000021174
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.274950
RefSeq NM_146150 XM_006502990 XM_006502993
OMIM
CCDS CCDS18460
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca