Version 5.4
Bos taurus Gene: BT.44915
Summary
InnateDB Gene IDBG-639493.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.44915
Gene Name nardilysin
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021174
Encoded Proteins
IDBP-691735
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000078618:
This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:95041110-95122769
Strand Forward strand
Band
Transcripts
ENSBTAT00000028220 ENSBTAP00000028220
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000078618
View Gene Order
ENSMUSG00000053510
View Gene Order
Cross-References
SwissProt
TrEMBL F1MXX5
UniProt Splice Variant
Entrez Gene 511254
UniGene Bt.44915
RefSeq NM_001206991 XM_005204544
HUGO HGNC:7995
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02008890 DAAA02008891
GenPept
RNA Seq Atlas 511254

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca