Version 5.4
Mus musculus Gene: Ebf2
Summary
InnateDB Gene IDBG-175890.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ebf2
Gene Name early B cell factor 2
Synonyms D14Ggc1e; EBF-2; Mmot1; O/E-3; OE-3
Species Mus musculus
Ensembl Gene ENSMUSG00000022053
Encoded Proteins
IDBP-175892
early B-cell factor 2
IDBP-716654
IDBP-718648
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000221818:
The protein encoded by this gene belongs to the COE (Collier/Olf/EBF) family of non-basic, helix-loop-helix transcription factors that have a well conserved DNA binding domain. The COE family proteins play an important role in variety of developmental processes. Studies in mouse suggest that this gene may be involved in the differentiation of osteoblasts. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:67233292-67430918
Strand Forward strand
Band D1
Transcripts
ENSMUST00000022637 ENSMUSP00000022637
ENSMUST00000177231
ENSMUST00000176161 ENSMUSP00000135500
ENSMUST00000176029 ENSMUSP00000135782
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0046872 metal ion binding
GO:0046983 protein dimerization activity
Biological Process
GO:0001709 cell fate determination
GO:0006351 transcription, DNA-templated
GO:0035563 positive regulation of chromatin binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0050873 brown fat cell differentiation
GO:0060612 adipose tissue development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000221818
View Gene Order
Cross-References
SwissProt O08792
TrEMBL
UniProt Splice Variant
Entrez Gene 13592
UniGene Mm.319947
RefSeq NM_001276387 NM_010095
OMIM
CCDS CCDS27228
HPRD
IMGT
MGI ID MGI:894332
MGI Symbol Ebf2
EMBL AK053013 AK139262 BC049188 BC050922 U71189 U82441 U92703
GenPept AAB58323 AAB58423 AAC64322 AAH49188 AAH50922 BAC35239 BAE23936
RNA Seq Atlas 13592

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca