Version 5.4
Mus musculus Gene: Asna1
Summary
InnateDB Gene IDBG-176096.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Asna1
Gene Name arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Synonyms 1810048H22Rik; ArsA
Species Mus musculus
Ensembl Gene ENSMUSG00000052456
Encoded Proteins
IDBP-176098
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198356:
This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:85017934-85025278
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000064314 ENSMUSP00000065337
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0046872 metal ion binding
Biological Process
GO:0006200 ATP catabolic process
GO:0006810 transport
GO:0045048 protein insertion into ER membrane
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005783 endoplasmic reticulum
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000198356
View Gene Order
ENSBTAG00000011837
Not yet available
Cross-References
SwissProt O54984
TrEMBL Q8VEI6
UniProt Splice Variant
Entrez Gene 56495
UniGene Mm.41475
RefSeq NM_019652
OMIM
CCDS CCDS40417
HPRD
IMGT
MGI ID MGI:1928379
MGI Symbol Asna1
EMBL AF039405 AF061177 AK171690 BC016453 BC018430 BC083335 CH466525
GenPept AAB94772 AAD15826 AAH16453 AAH18430 AAH83335 BAE42614 EDL10985
RNA Seq Atlas 56495

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca