Version 5.4
Mus musculus Gene: Ddah2
Summary
InnateDB Gene IDBG-176274.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ddah2
Gene Name dimethylarginine dimethylaminohydrolase 2
Synonyms 1110003M04Rik; AU019324; AW413173; Ddah; DDAH-2; DDAHII; G6a; NG30
Species Mus musculus
Ensembl Gene ENSMUSG00000007039
Encoded Proteins
IDBP-176276
dimethylarginine dimethylaminohydrolase 2
IDBP-628008
dimethylarginine dimethylaminohydrolase 2
IDBP-628009
dimethylarginine dimethylaminohydrolase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000213722:
This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:35059035-35062095
Strand Forward strand
Band B1
Transcripts
ENSMUST00000007255 ENSMUSP00000007255
ENSMUST00000174493 ENSMUSP00000134072
ENSMUST00000173520 ENSMUSP00000134595
ENSMUST00000173562
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016403 dimethylargininase activity
GO:0016597 amino acid binding
GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
Biological Process
GO:0000052 citrulline metabolic process
GO:0006525 arginine metabolic process
GO:0006527 arginine catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000213722
View Gene Order
ENSBTAG00000013530
Not yet available
Cross-References
SwissProt
TrEMBL G3UZR0
UniProt Splice Variant
Entrez Gene 51793
UniGene
RefSeq NM_001190449 NM_016765 XM_006524612
OMIM
CCDS CCDS50082 CCDS57070
HPRD
IMGT
MGI ID MGI:1859016
MGI Symbol Ddah2
EMBL AC087117
GenPept
RNA Seq Atlas 51793

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca