InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Gpr55

Summary

InnateDB Gene

IDBG-176329.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gpr55

Gene Name

G protein-coupled receptor 55

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000049608

Encoded Proteins

IDBP-176331

G protein-coupled receptor 55

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135898:
Members of the G protein-coupled receptor (GPR) family, such as GPR55, play important roles in signal transduction from the external environment to the inside of the cell (Sawzdargo et al., 1999 [PubMed 9931487]).[supplied by OMIM, Apr 2008]
This gene belongs to the G-protein-coupled receptor superfamily. The encoded integral membrane protein is a likely cannabinoid receptor. It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways. [provided by RefSeq, Aug 2013]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:85938318-85961007

Strand

Reverse strand

Band

Transcripts

ENSMUST00000086975

ENSMUSP00000084196

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0004949	cannabinoid receptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007202	activation of phospholipase C activity
GO:0035025	positive regulation of Rho protein signal transduction
GO:0038171	cannabinoid signaling pathway
GO:0045453	bone resorption
GO:0045671	negative regulation of osteoclast differentiation
GO:0070374	positive regulation of ERK1 and ERK2 cascade