Version 5.4
Mus musculus Gene: Wdr83
Summary
InnateDB Gene IDBG-176692.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wdr83
Gene Name WD repeat domain containing 83
Synonyms 1500041N16Rik; Morg1
Species Mus musculus
Ensembl Gene ENSMUSG00000005150
Encoded Proteins
IDBP-176694
WD repeat domain containing 83
IDBP-538581
WD repeat domain containing 83
IDBP-535654
WD repeat domain containing 83
IDBP-537309
WD repeat domain containing 83
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123154:
This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:85075035-85081306
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000093357 ENSMUSP00000091048
ENSMUST00000136696
ENSMUST00000131909
ENSMUST00000145880
ENSMUST00000142201 ENSMUSP00000122737
ENSMUST00000146900
ENSMUST00000152186
ENSMUST00000152785 ENSMUSP00000122127
ENSMUST00000149050 ENSMUSP00000121568
ENSMUST00000135463
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000375 RNA splicing, via transesterification reactions
GO:0006397 mRNA processing
Cellular Component
GO:0005681 spliceosomal complex
GO:0005737 cytoplasm
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000123154
View Gene Order
ENSBTAG00000006245
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.334680
RefSeq NM_026399
OMIM
CCDS CCDS22493
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca