Version 5.4
Mus musculus Gene: Il17re
Summary
InnateDB Gene IDBG-176930.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Il17re
Gene Name interleukin 17 receptor E
Synonyms AA589509; IL-17RE; Il25r
Species Mus musculus
Ensembl Gene ENSMUSG00000043088
Encoded Proteins
IDBP-176932
interleukin 17 receptor E
IDBP-176936
interleukin 17 receptor E
IDBP-176938
interleukin 17 receptor E
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 21993849
Il17re is a receptor specific to Il17c that regulates early innate immunity to intestinal pathogens in colon epithelial cells.
InnateDB Annotation from Orthologs
Summary
PMID 21993849
[Homo sapiens] IL17RE is a receptor specific to IL17C that regulates early innate immunity to intestinal pathogens in colon epithelial cells. (Demonstrated in mice)
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163701:
This gene encodes a protein that shares limited similarity with the interleukin-17 receptor. The function of the encoded protein has not yet been determined. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:113458484-113470751
Strand Forward strand
Band E3
Transcripts
ENSMUST00000058548 ENSMUSP00000062103
ENSMUST00000053569 ENSMUSP00000054378
ENSMUST00000101065 ENSMUSP00000098626
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006954 inflammatory response
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000163701
View Gene Order
ENSBTAG00000010833
Not yet available
Cross-References
SwissProt Q8BH06
TrEMBL
UniProt Splice Variant
Entrez Gene 57890
UniGene Mm.131781
RefSeq NM_001034029 NM_001034031 NM_145826
OMIM
CCDS CCDS20420 CCDS20421
HPRD
IMGT
MGI ID MGI:1889371
MGI Symbol Il17re
EMBL AF458068 AK046302 AK046713 AK078876 AK169498 BC026737 BC069861 DQ092339 DQ092340 DQ092341
GenPept AAH26737 AAH69861 AAM77572 AAZ85958 AAZ85959 AAZ85960 BAC32678 BAC32842 BAC37436 BAE41201
RNA Seq Atlas 57890

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca