Version 5.4
| Mus musculus Gene: Rhobtb2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-177688.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Rhobtb2 | ||||||||
| Gene Name | Rho-related BTB domain containing 2 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000022075 | ||||||||
| Encoded Proteins |
Rho-related BTB domain containing 2
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000008853:
The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 14:69784990-69805530 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | D2 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Signaling by Rho GTPases pathway
Rho GTPase cycle pathway
Signal Transduction pathway
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| KEGG |
Ubiquitin mediated proteolysis pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Rho GTPase cycle pathway
Signaling by Rho GTPases pathway
Signal Transduction pathway
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| KEGG |
Ubiquitin mediated proteolysis pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q91V93 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 246710 | ||||||||
| UniGene | Mm.397418 | ||||||||
| RefSeq | NM_153514 XM_006519022 XM_006519023 XM_006519024 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS27244 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:2180557 | ||||||||
| MGI Symbol | Rhobtb2 | ||||||||
| EMBL | AF420001 AF420002 AK038196 BC026836 BC056954 | ||||||||
| GenPept | AAH26836 AAH56954 AAL16061 AAL16063 BAC29946 | ||||||||
| RNA Seq Atlas | 246710 | ||||||||