Bos taurus Gene: BT.88914
Summary
InnateDB Gene IDBG-634978.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.88914
Gene Name rho-related BTB domain-containing protein 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000031916
Encoded Proteins
rho-related BTB domain-containing protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000008853:
The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:70834527-70896918
Strand Reverse strand
Band
Transcripts
ENSBTAT00000045250 ENSBTAP00000042655
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
Cellular Component
GO:0005622 intracellular
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Rho GTPase cycle pathway
Signaling by Rho GTPases pathway
Signal Transduction pathway
Signaling by Rho GTPases pathway
Rho GTPase cycle pathway
Signal Transduction pathway
KEGG
Ubiquitin mediated proteolysis pathway
Ubiquitin mediated proteolysis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.105779 Bt.34549 Bt.88914
RefSeq NM_001103104 XM_005200217 XM_005210264
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas