Version 5.4
Mus musculus Gene: Slc39a14
Summary
InnateDB Gene IDBG-178315.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc39a14
Gene Name solute carrier family 39 (zinc transporter), member 14
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000022094
Encoded Proteins
IDBP-178317
solute carrier family 39 (zinc transporter), member 14
IDBP-178321
solute carrier family 39 (zinc transporter), member 14
IDBP-533681
solute carrier family 39 (zinc transporter), member 14
IDBP-537698
solute carrier family 39 (zinc transporter), member 14
IDBP-541691
solute carrier family 39 (zinc transporter), member 14
IDBP-533835
solute carrier family 39 (zinc transporter), member 14
IDBP-532611
solute carrier family 39 (zinc transporter), member 14
IDBP-541689
solute carrier family 39 (zinc transporter), member 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104635:
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A14 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:70303469-70351425
Strand Reverse strand
Band D2
Transcripts
ENSMUST00000068044 ENSMUSP00000066108
ENSMUST00000022688 ENSMUSP00000022688
ENSMUST00000152067 ENSMUSP00000119040
ENSMUST00000155825
ENSMUST00000145040
ENSMUST00000146453
ENSMUST00000152202
ENSMUST00000152442 ENSMUSP00000117010
ENSMUST00000143153 ENSMUSP00000122816
ENSMUST00000151011 ENSMUSP00000118319
ENSMUST00000127000 ENSMUSP00000117792
ENSMUST00000139284 ENSMUSP00000122615
ENSMUST00000142598
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005385 zinc ion transmembrane transporter activity
GO:0015093 ferrous iron transmembrane transporter activity
GO:0046873 metal ion transmembrane transporter activity
Biological Process
GO:0006826 iron ion transport
GO:0006829 zinc ion transport
GO:0006882 cellular zinc ion homeostasis
GO:0015684 ferrous iron transport
GO:0030001 metal ion transport
GO:0055085 transmembrane transport
GO:0071577 zinc ion transmembrane transport
GO:0071578 zinc ion transmembrane import
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000104635
View Gene Order
ENSBTAG00000019225
Not yet available
Pathways
NETPATH
REACTOME
REACT_217615
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_198240
Zinc influx into cells by the SLC39 gene family pathway
REACT_243781
Zinc transporters pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_251299
Metal ion SLC transporters pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20603
Zinc influx into cells by the SLC39 gene family pathway
REACT_20547
Metal ion SLC transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_20530
Zinc transporters pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_222460
SLC-mediated transmembrane transport pathway
REACT_208122
Zinc transporters pathway
REACT_221584
Metal ion SLC transporters pathway
REACT_223103
Transmembrane transport of small molecules pathway
REACT_219894
Zinc influx into cells by the SLC39 gene family pathway
REACT_212003
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.270647
RefSeq NM_001135151 NM_001135152 NM_144808 XM_006518785 XM_006518786 XM_006518788 XM_006518789 XM_006518791
OMIM
CCDS CCDS36969 CCDS49536
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca