InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Slc30a5

Summary

InnateDB Gene

IDBG-178710.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc30a5

Gene Name

solute carrier family 30 (zinc transporter), member 5

Synonyms

1810010K08Rik; AF233321; ZnT-5; ZNT5; Zntl1; ZTL1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000021629

Encoded Proteins

IDBP-178712

solute carrier family 30 (zinc transporter), member 5

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000145740:
This gene encodes a member of the SLC30A/ZnT family of zinc transporter proteins. ZnT proteins mediate both cellular zinc efflux and zinc sequestration into membrane-bound organelles. The encoded protein plays a role in the early secretory pathway as a heterodimer with zinc transporter 6, and may also regulate zinc sequestration into secretory granules of pancreatic beta cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. [provided by RefSeq, Oct 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:100802649-100833427

Strand

Reverse strand

Band

Transcripts

ENSMUST00000067246

ENSMUSP00000065764

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005385	zinc ion transmembrane transporter activity
GO:0008324	cation transmembrane transporter activity

Biological Process

GO:0006812	cation transport
GO:0006824	cobalt ion transport
GO:0006829	zinc ion transport
GO:0006882	cellular zinc ion homeostasis
GO:0010043	response to zinc ion
GO:0055085	transmembrane transport
GO:0071577	zinc ion transmembrane transport

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005794	Golgi apparatus
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0030141	secretory granule