Homo sapiens Gene: SLC30A5 | |||||||||||||||||||||
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Summary | |||||||||||||||||||||
InnateDB Gene | IDBG-25156.6 | ||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||
Gene Symbol | SLC30A5 | ||||||||||||||||||||
Gene Name | solute carrier family 30 (zinc transporter), member 5 | ||||||||||||||||||||
Synonyms | |||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||
Ensembl Gene | ENSG00000145740 | ||||||||||||||||||||
Encoded Proteins |
solute carrier family 30 (zinc transporter), member 5
solute carrier family 30 (zinc transporter), member 5
solute carrier family 30 (zinc transporter), member 5
solute carrier family 30 (zinc transporter), member 5
solute carrier family 30 (zinc transporter), member 5
solute carrier family 30 (zinc transporter), member 5
solute carrier family 30 (zinc transporter), member 5
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Protein Structure | |||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
Summary |
This gene encodes a member of the SLC30A/ZnT family of zinc transporter proteins. ZnT proteins mediate both cellular zinc efflux and zinc sequestration into membrane-bound organelles. The encoded protein plays a role in the early secretory pathway as a heterodimer with zinc transporter 6, and may also regulate zinc sequestration into secretory granules of pancreatic beta cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. [provided by RefSeq, Oct 2011] |
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Gene Information | |||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||
Genomic Location | Chromosome 5:69093646-69131069 | ||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||
Band | q13.1 | ||||||||||||||||||||
Transcripts | |||||||||||||||||||||
Interactions | |||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||
NETPATH | |||||||||||||||||||||
REACTOME |
Zinc efflux and compartmentalization by the SLC30 family pathway
Metal ion SLC transporters pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Insulin processing pathway
Transmembrane transport of small molecules pathway
Metabolism of proteins pathway
Zinc transporters pathway
Peptide hormone metabolism pathway
SLC-mediated transmembrane transport pathway
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KEGG | |||||||||||||||||||||
INOH | |||||||||||||||||||||
PID NCI | |||||||||||||||||||||
Cross-References | |||||||||||||||||||||
SwissProt | |||||||||||||||||||||
TrEMBL | |||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
UniGene | Hs.631975 | ||||||||||||||||||||
RefSeq | NM_001251969 NM_022902 NM_024055 XM_005248569 | ||||||||||||||||||||
HUGO | |||||||||||||||||||||
OMIM | |||||||||||||||||||||
CCDS | CCDS34173 CCDS3996 CCDS58955 | ||||||||||||||||||||
HPRD | 06381 | ||||||||||||||||||||
IMGT | |||||||||||||||||||||
EMBL | |||||||||||||||||||||
GenPept | |||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||