Version 5.4
Mus musculus Gene: Afap1l2
Summary
InnateDB Gene IDBG-179434.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Afap1l2
Gene Name actin filament associated protein 1-like 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000025083
Encoded Proteins
IDBP-257792
actin filament associated protein 1-like 2
IDBP-400808
actin filament associated protein 1-like 2
IDBP-400807
actin filament associated protein 1-like 2
IDBP-540353
actin filament associated protein 1-like 2
IDBP-542464
actin filament associated protein 1-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169129:
Gene Information
Type Protein coding
Genomic Location Chromosome 19:56912361-57008228
Strand Reverse strand
Band D2
Transcripts
ENSMUST00000111584 ENSMUSP00000107210
ENSMUST00000118800 ENSMUSP00000113745
ENSMUST00000122359 ENSMUSP00000112387
ENSMUST00000155467
ENSMUST00000148049 ENSMUSP00000120490
ENSMUST00000126964 ENSMUSP00000123400
ENSMUST00000132851
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0017124 SH3 domain binding
GO:0030296 protein tyrosine kinase activator activity
GO:0042169 SH2 domain binding
Biological Process
GO:0006954 inflammatory response
GO:0007346 regulation of mitotic cell cycle
GO:0032675 regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway
GO:0045893 positive regulation of transcription, DNA-templated
GO:0061098 positive regulation of protein tyrosine kinase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016235 aggresome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000169129
View Gene Order
ENSBTAG00000004895
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q5DTU0
TrEMBL D3YYQ6 D3YZD3
UniProt Splice Variant
Entrez Gene 226250
UniGene Mm.226284
RefSeq NM_146102 NM_001177796 NM_001177797
OMIM
CCDS CCDS29924 CCDS50476 CCDS50477
HPRD
IMGT
MGI ID MGI:2147658
MGI Symbol Afap1l2
EMBL AC125150 AC161518 AK087449 AK220430 BC031515
GenPept AAH31515 BAC39879 BAD90264
RNA Seq Atlas 226250

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca