Version 5.4
Mus musculus Gene: Abcf1
Summary
InnateDB Gene IDBG-179786.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Abcf1
Gene Name ATP-binding cassette, sub-family F (GCN20), member 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038762
Encoded Proteins
IDBP-179788
ATP-binding cassette, sub-family F (GCN20), member 1
IDBP-628322
ATP-binding cassette, sub-family F (GCN20), member 1
IDBP-628323
ATP-binding cassette, sub-family F (GCN20), member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204574:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:35956819-35969761
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000043757 ENSMUSP00000036881
ENSMUST00000087205
ENSMUST00000173111
ENSMUST00000173125
ENSMUST00000173090
ENSMUST00000174834
ENSMUST00000174128 ENSMUSP00000134716
ENSMUST00000172661 ENSMUSP00000134092
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008494 translation activator activity
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0043022 ribosome binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006200 ATP catabolic process
GO:0006413 translational initiation
GO:0045727 positive regulation of translation
Cellular Component
GO:0005635 nuclear envelope
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0016020 membrane
GO:0042788 polysomal ribosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000204574
View Gene Order
ENSBTAG00000006927
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.329022
RefSeq NM_013854
OMIM
CCDS CCDS28713
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca