Version 5.4
Mus musculus Gene: Esd
Summary
InnateDB Gene IDBG-180328.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Esd
Gene Name esterase D/formylglutathione hydrolase
Synonyms Es-10; Es10; FGH; sid478
Species Mus musculus
Ensembl Gene ENSMUSG00000021996
Encoded Proteins
IDBP-180330
esterase D/formylglutathione hydrolase
IDBP-718780
IDBP-718628
IDBP-716765
IDBP-717405
IDBP-718432
IDBP-718078
IDBP-717022
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139684:
This gene encodes a serine hydrolase that belongs to the esterase D family. The encoded enzyme is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of sialic acids. This gene is used as a genetic marker for retinoblastoma and Wilson's disease. [provided by RefSeq, Feb 2009]
This gene encodes a serine hydrolase that belongs to the esterase D family. The encoded enzyme is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of sialic acids. This gene is used as a genetic marker for retinoblastoma and Wilson\'s disease. [provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:74732297-74750765
Strand Forward strand
Band D3
Transcripts
ENSMUST00000022573 ENSMUSP00000022573
ENSMUST00000177137 ENSMUSP00000135818
ENSMUST00000176188
ENSMUST00000176726 ENSMUSP00000135708
ENSMUST00000177181 ENSMUSP00000135035
ENSMUST00000175712 ENSMUSP00000134932
ENSMUST00000176957 ENSMUSP00000135394
ENSMUST00000177283 ENSMUSP00000135063
ENSMUST00000177445
ENSMUST00000176484
ENSMUST00000175887 ENSMUSP00000135244
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008236 serine-type peptidase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0018738 S-formylglutathione hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0046294 formaldehyde catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000139684
View Gene Order
ENSBTAG00000003415
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.377952
RefSeq NM_001285423 NM_016903 XM_001475316 XM_006518543
OMIM
CCDS CCDS36975 CCDS70603
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca